Symptoms And Treatment Of Autoimmune Diseases - 834 Words

2.Classification of autoimmune diseases Autoimmune diseases are caused by auto-antibodies, according to auto-antibodies can be divided into: organ-specific, which affects one organ; non-organ specific, which are a multisystem disease. 2.1. Organ-specific 2.1.1. Autoimmune thyroid diseases They are a common cause of thyroid disorders and it is caused by auto-antibodies against the thyroid stimulating hormone receptor (TSH), intracytoplasmic antigen or thyroglobulin. 2.1.1.1.Grave s disease Grave s disease is the most known cause of thyrotoxicosis. this is due to auto-antibodies against TSH receptors that result in stimulation of thyroid gland for secretion of thyroid hormone, this excess in hormone secretion lead to hyperthyroidism. The common clinical pictures of grave s are a goiter, eye signs, and hyperthyroidism. Hyperthyroidism are manifested by weight loss, diarrhea, nervousness, palpitation, sweating, heat intolerance and insomnia. 2.1.1.2. Hashimoto s thyroiditis Hashimoto s thyroiditis is the frequent cause for hypothyroidism, which known as myxedema. It is caused by auto-antibodies to Thyroglobulin and thyroid peroxidase, these two proteins are required for the production of hormone. Clinically, patients with hypothyroidism complain of weight gain, constipation, cold intolerance, muscle ache, dry skin, bradycardia, somnolence and heavy menses. 2.1.1.3.Diabetes mellitus (type 1) Islet cells in the pancreas are known to be the chief for production of insulinShow MoreRelatedDiscussion. Cause. Systemic Lupus Erythematosus Is Complex1711 Words   |  7 Pages Discussion Cause Systemic Lupus Erythematosus is complex autoimmune disease caused by a combination of genetic, epigenetic, and environmental factors. The body’s autoimmune cells fail to distinguish a diseased cell or foreign organism from its own healthy cells. 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